Objectives
- To follow biologically informed plasma markers of disease through clinical time course of critical illness
- To compare these markers between intervention groups
- To predict outcomes using these markers of disease
- To validate known disease associations in a novel population (critical illness)
Tasks
- Decentralized sample collection, with centralized sample storage
- Centres categorized
- Level 3 – Able to collect, process, and store samples for extended periods of time (archival storage)
- Initially only TGH through TLTP biobank infrastructure
- Level 2 – Able to collect, process, and store some samples for at least 2 weeks
- Level 1 – Able to collect/process samples, but no -80 °C freezer access
- Store limited samples for 48-72h
- Level 3 – Able to collect, process, and store samples for extended periods of time (archival storage)
- The PRACTICAL biobank will use the infrastructure of the TLTP biobank and will therefore use their data management system
- Clinical data will be collected via the PRACTICAL case reporting form (CRF)
Group Members

MD, PhD, FRCPC, FACC

MD, DPhil, FRCPC

MD, MAS

MD, PhD, FRCPC

MD, MSc, FACS, FRCSC

M.Sc. MD. FRCPC

MD, PhD

MD, MS, FECMM, FRCP(Edin)

MD, FRCPC

MD, MPH, FRCPC
MD, PhD, FRCPC

MD, MHS

MD, PhD, FRCPC

MD, MSc, FRCPC

CM, FRSC, MASc, MD

MD, PhD, FRCPC, ABOM Diplomate

MD, FRCPC, FACP, FCCP, FCCM