Dr. Claudia Dos Santos

Dr. dos Santos is a Professor of Medicine within the Temerty Faculty of Medicine with a clinical appointment as a staff critical care intensivist at Unity Health Toronto (UHT), a university hospital affiliated with the University of Toronto. Dr. dos Santos previously held the Pitts Research Chair in Acute Care and Emergency Medicine and now holds a Tier 1 Canada Research Chair for Translational Molecular Critical Care. She is a scientist at the Keenan Research Centre for Biomedical Science. Her research is aimed at building a world-class program in translational molecular critical care with three distinct areas of expertise: 1) patient-based discovery (omics/bioinformatics); 2) in-vitro mechanistic research (cell models); and 3) in-vivo preclinical research (transgenic animal models). Dr. dos Santos is past-scientific director of the Canadian Critical Care Society and co-director of the Centre for Research and Applications in Fluidic Technologies (CRAFT), a collaboration between the University of Toronto, the National Research Council of Canada and UHT. Dr. dos Santos created the Critical Care Medicine Biobank at Unity Health and leads the PREcision meDIcine for CriTical Care (PREDICT) program, to advance translational molecular critical care using precision diagnostics, machine learning and artificial intelligence. She is also the project lead for ARIATNE, Advanced RNA-Intelligence for Accelerated Therapeutic Nanoparticle Engineering, a collaboration with the Nanomedicine Innovation Network (NMIN) that will translate knowledge gained in PREDICT into personalized RNA-therapies for rapid response to infection and pandemic preparedness. She is the co-founder of the student owned NorthMiRs, a start-up dedicated to develop RNA and gene-based nanotherapies for the treatment of sepsis and acute respiratory distress syndrome.