Documents

Kindly be aware that the protocols and other documents provided on this page are intended for general reference purposes. For actual implementation purposes at study sites, please consult the current REB/IRB/LEC approved versions for your site. Should you have any questions, please do not hesitate to email info@practicalplatform.org

Master

  • 1. PRACTICAL Platform Trial - Summary

    • (pdf:720KB)

  • 2. PRACTICAL Master Protocol

    • (pdf:1.1MB)

  • 3. PRACTICAL Master Statistical Analysis Plan

    • (pdf:612KB)

  • SOP Evaluation Process for Ancillary Analyses

    • (pdf:357KB)

  • The PRACTICAL Randomized Controlled Trial Publication Policy

    • (pdf:433KB)

CORT-E2

FAST-3

FLUDRO

IMPROV

  • IMPROV Protocol

    • (pdf:1.3MB)

  • Links and QR Codes to IMPROV Slides & Videos

    • (pdf:79KB)

IMV

  • 1. IMV Strategies Protocol Summary

    • (pdf:571KB)

  • 2. IMV Strategies Domain Protocol v2.0

    • (pdf:1.5MB)

  • 2. IMV Strategies Domain Protocol v3.0

    • (pdf:1.2MB)

  • 3a. IMV Strategies Domain Intervention Appendix_LPV v2.0

    • (pdf:804KB)

  • 3a. IMV Strategies Domain Intervention Appendix_LPV v3.0

    • (pdf:813KB)

  • 3b. IMV Strategies Domain Intervention Appendix_DPL v2.0

    • (pdf:975KB)

  • 3b. IMV Strategies Domain Intervention Appendix_DPL v3.0

    • (pdf:1.0MB)

  • 3c. IMV Strategies Domain Intervention Appendix_LDPVS v1.0

    • (pdf:1.2MB)

  • 3d. IMV Strategies Domain Intervention Appendix_CAVIARDS_v.1.0

    • (pdf:1.3MB)

  • 3e. IMV Strategies Domain EIT Intervention Appendix_v.1.0

    • (pdf:369KB)

  • IMV strategies domain video slides:  DPL Strategy

    • (pdf:1.3MB)

  • IMV strategies domain video slides:  LDPVS Strategy

    • (pdf:1.6MB)

  • IMV strategies domain video slides:  LPV Strategy

    • (pdf:1.1MB)

  • IMV strategies domain video slides:  Pre-randomization standardized ventilator settings

    • (pdf:707KB)

  • IMV Strategies Protocol Summary v3

    • (pdf:187KB)

IMV-ECLS

  • IMV-ECLS Domain Protocol v1.0

    • (pdf:1.7MB)

  • IMV-ECLS_PEEP-10 Intervention Appendix_v.1.0

    • (pdf:1.2MB)

  • IMV-ECLS_PEEP-20 Intervention Appendix_v.1.0

    • (pdf:1.0MB)

  • IMV-ECLS_PEEP-AOP Intervention Appendix_v.1.0

    • (pdf:1.0MB)

EXPAND-ECLS (previously ULTIMATE)

  • 1. EXPAND-ECLS Protocol Summary

    • (pdf:209KB)

  • 2. EXPAND-ECLS Domain Protocol

    • (pdf:1.4MB)

Physiology Working Group

  • Basic Mechanics and Non-invasive Drive and Effort

    • (pdf:862KB)

  • Diaphragm Ultrasound

    • (pdf:550KB)

  • Maximum Inspiratory Pressure

    • (pdf:461KB)